compound II [PMID: 21329883]

Ligand id: 9579

Name: compound II [PMID: 21329883]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 95.75
Molecular weight 535.29
XLogP 2.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Ou YH, Torres M, Ram R, Formstecher E, Roland C, Cheng T, Brekken R, Wurz R, Tasker A, Polverino T et al.. (2011)
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Mol. Cell, 41 (4): 458-70. [PMID:21329883]