compound 2f [Jiang et al., 2018]

Ligand id: 9810

Name: compound 2f [Jiang et al., 2018]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 12
Topological polar surface area 146.37
Molecular weight 556.23
XLogP 3.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Jiang X-Y, Chen T-K, Zhou J-T, He S-Y, Yang H-Y, Chen Y, Qu W, Feng F, Sun H-P. (2018)
Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer’s Disease Drug Discovery.
ACS Med. Chem. Lett., Article ASAP.