Synonyms: Synarel®
nafarelin is an approved drug (FDA (1990))
Compound class:
Peptide or derivative
Comment: Nafarelin is a gonadotropin releasing hormone receptor agonist. The structure shown here is from PubChem CID 25077405.
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Peptide Sequence | |
XHWSYXLRPG | |
H-Pyr-His-Trp-Ser-Tyr-D-2Nal-Leu-Arg-Pro-Gly-NH2 |
HELM Notation | |
PEPTIDE1{[Glp].H.W.S.Y.[*C(=O)[C@@H](Cc1ccc2ccccc2c1)N* |$_R2;;;;;;;;;;;;;;;;_R1$|].L.R.P.G.[am]}$$$$ |
Chemical Modification | |
C terminal amidation; N-terminal pyroglutamate; 3-(2-naphthyl)-D-alanine (D-3-naphthylalanine; D-Nal) substitution at residue 6 |
Download 2D Structure | |
Canonical SMILES | Download |
Isomeric SMILES | Download |
InChI standard identifier | Download |
InChI standard key | Download |
Molecular structure representations generated using Open Babel