IL-12A   Click here for help

GtoPdb Ligand ID: 5001

Synonyms: IL-12 p35 | interleukin-12A | NKSF1
Immunopharmacology Ligand
Comment: This is the alpha subunit of the active IL-12 hetreodimer.
Species: Human
Is a component of
Peptide Sequence Click here for help
RNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRET
SFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSS
LEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
Post-translational Modification
Predicted N-linked glycosylation of asparagine residues at positions 71 and 85; disulphide bond formation between cysteine residues at positions 42 and 174, and 63 and 101. In the heterodimer IL12A/IL12B an interchain disulphide bond is formed between cysteine residues at position 74 of the alpha chain and 177 of the beta chain