Synonyms: LY-3214996 | LY3214996
Compound class:
Synthetic organic
Comment: LY3214996 is an ERK1/2 inhibitor that is in early stage clinical development for the potential treatment of advanced non-hematological tumours, in particular for malignancies carrying activating MAPK pathway alterations, and which are refractory to RAF and MEK inhibitors.
(Note: ERK1= MAPK3, ERK2= MAPK1). The chemical structure of LY3214996 matches that for the INN compound temuterkib that was surfaced in WHO Proposed list 125 in July 2021. |
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InChI standard identifier | Download |
InChI standard key | Download |
Molecular structure representations generated using Open Babel