AG 1024

Ligand id: 5912

Name: AG 1024

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 67.81
Molecular weight 304.02
XLogP 3.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(3-bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile
Synonyms
AG-1024 | AG1024 | tyrphostin AG 1024
Database Links
CAS Registry No. 65678-07-1
ChEMBL Ligand CHEMBL2218926
GtoPdb PubChem SID 178102535
PubChem CID 2044
Search Google for chemical match using the InChIKey ABBADGFSRBWENF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ABBADGFSRBWENF
Search UniChem for chemical match using the InChIKey ABBADGFSRBWENF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ABBADGFSRBWENF
Comments
AG 1024 is a selective inhibitor of IGF1R (Insulin-like growth factor I receptor) and inhibits insulin-stimulated cellular proliferation [3].