BPIQ-I

Ligand id: 5939

Name: BPIQ-I

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 55.63
Molecular weight 353.03
XLogP 3.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(3-bromophenyl)-3-methyl-3H-imidazo[4,5-g]quinazolin-8-amine
Database Links
CAS Registry No. 174709-30-9
ChEMBL Ligand CHEMBL174426
PubChem CID 2427
Search Google for chemical match using the InChIKey YAMAGACQNDAKFB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YAMAGACQNDAKFB
Search UniChem for chemical match using the InChIKey YAMAGACQNDAKFB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YAMAGACQNDAKFB
Comments
BPIQ-I is a cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) [3].