CZC 24832

Ligand id: 6653

Name: CZC 24832

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 123.65
Molecular weight 364.11
XLogP 0.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-{2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl}-N-tert-butylpyridine-3-sulfonamide
Synonyms
CZC-24832 | CZC24832
Database Links
CAS Registry No. 1159824-67-5 (source: Scifinder)
ChEMBL Ligand CHEMBL2064571
PubChem CID 42623951
Search Google for chemical match using the InChIKey RXRZPHQBTHQXSV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RXRZPHQBTHQXSV
Search UniChem for chemical match using the InChIKey RXRZPHQBTHQXSV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RXRZPHQBTHQXSV
Comments
CZC24832 is the first reported selective PI3Kγ inhibitor [1]. The activity of CZC24832 has been investigated in preclinical studies.