enoxaparin

Ligand id: 6811

Name: enoxaparin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 39
Hydrogen bond donors 15
Rotatable bonds 22
Topological polar surface area 652.39
Molecular weight 1134.01
XLogP -13.27
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
IUPAC Name
6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-3-[5-(6-carboxy-4,5-dihydroxy-3-sulfooxyoxan-2-yl)oxy-6-(hydroxymethyl)-3-(sulfoamino)-4-sulfooxyoxan-2-yl]oxy-4-hydroxy-5-sulfooxyoxane-2-carboxylic acid
International Nonproprietary Names
INN number INN
5452 enoxaparin sodium
Synonyms
Clexane® | enoxaparin sodium | Lovenox® | PK-10169 | RP-54563
Database Links
CAS Registry No. 679809-58-6
ChEMBL Ligand CHEMBL1201476
DrugBank Ligand DB01225
PubChem CID 772
Search Google for chemical match using the InChIKey HTTJABKRGRZYRN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HTTJABKRGRZYRN
Search PubMed clinical trials enoxaparin sodium
Search PubMed titles enoxaparin sodium
Search PubMed titles/abstracts enoxaparin sodium
Search UniChem for chemical match using the InChIKey HTTJABKRGRZYRN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HTTJABKRGRZYRN
Wikipedia Enoxaparin
Comments
A Low-Molecular-Weight Heparin antithrombin-III activator. It consists of fractionated material from pig mucosa but the PubChem structure represents the major form.

Biosimilar drugs: The EMA approved enoxaparin biosimilars named Inhixa and Thorinane in 2016.