methazolamide

Ligand id: 6828

Name: methazolamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 126.51
Molecular weight 236
XLogP -1.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
IUPAC Name
N-(3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide
International Nonproprietary Names
INN number INN
882 methazolamide
Synonyms
methenamide | Neptazane®
Database Links
CAS Registry No. 554-57-4
ChEMBL Ligand CHEMBL1335656
DrugBank Ligand DB00703
PubChem CID 4100
Search Google for chemical match using the InChIKey FLOSMHQXBMRNHR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FLOSMHQXBMRNHR
Search PubMed clinical trials methazolamide
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Search UniChem for chemical match using the InChIKey FLOSMHQXBMRNHR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FLOSMHQXBMRNHR
SynPHARM 78861 (in complex with carbonic anhydrase 1)
Wikipedia Methazolamide
Comments
Inhibits carbonic anhydrases. This compound is also represented on ChEMBL by the entry with ID CHEMBL19.