AZD5904

Ligand id: 7728

Name: AZD5904

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 102.34
Molecular weight 252.07
XLogP 0.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[[(2R)-oxolan-2-yl]methyl]-2-sulfanylidene-7H-purin-6-one
Synonyms
AZD 5904 | AZD-5904
Database Links
PubChem CID 10264211
Search Google for chemical match using the InChIKey RSPDBEVKURKEII-ZCFIWIBFSA-N
Search Google for chemicals with the same backbone RSPDBEVKURKEII
Search UniChem for chemical match using the InChIKey RSPDBEVKURKEII-ZCFIWIBFSA-N
Search UniChem for chemicals with the same backbone RSPDBEVKURKEII
Comments
AZD5904 is compound TX4 in [1]. AZD5904 was developed as a myeloperoxidase (MPO; P05164) inhibitor, but was abandoned as a clinical candidate for the treatment of inflammatory conditions involving oxidative stress. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.