AZD7268

Ligand id: 7824

Name: AZD7268

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 97.8
Molecular weight 498.21
XLogP 4.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(2-hydroxyethyl)-N-methyl-4-[quinolin-8-yl-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl]benzamide
Synonyms
AZ 12488024 | AZ-12488024 | AZ12488024 | AZD 7268 | AZD-7268
Database Links
ChEMBL Ligand CHEMBL1946618
GtoPdb PubChem SID 223366155
PubChem CID 24772484
Search Google for chemical match using the InChIKey ZJKUETLEJYCOBO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZJKUETLEJYCOBO
Search UniChem for chemical match using the InChIKey ZJKUETLEJYCOBO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZJKUETLEJYCOBO
Comments
AZD7268 is a potent, selective and reversible CNS‐penetrating and orally bioavailable δ-opioid receptor agonist.
This compound was in the AstraZeneca/MRC repurposing list from 2011.