danirixin

Ligand id: 8500

Name: danirixin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 115.91
Molecular weight 441.09
XLogP 4.44
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-[4-chloro-2-hydroxy-3-[(3S)-piperidin-3-yl]sulfonylphenyl]-3-(3-fluoro-2-methylphenyl)urea
International Nonproprietary Names
INN number INN
9559 danirixin
Synonyms
GSK-1325756B | GSK1325756 | GSK1325756B
Database Links
CAS Registry No. 954126-98-8
ChEMBL Ligand CHEMBL3039531
PubChem CID 24780598
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Comments
Danirixin (GSK-1325756B) is being developed as a clinically efficacious antagonist of the CXCR2 chemokine receptor [1].