erdafitinib

Ligand id: 9039

Name: erdafitinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 77.33
Molecular weight 446.24
XLogP 3.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N'-(3,5-dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine
International Nonproprietary Names
INN number INN
10147 erdafitinib
Synonyms
compound 4 [WO2011135376] [1] | JNJ-42756493
Database Links
PubChem CID 67462786
RCSB PDB Ligand 5SF
Search Google for chemical match using the InChIKey OLAHOMJCDNXHFI-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey OLAHOMJCDNXHFI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone OLAHOMJCDNXHFI
Comments
Erdafitinib is an investigational compound which is a pan inhibitor of the fibroblast growth factor receptor tyrosine kinases, FGFR1-4 [1].