phosphodiesterase 6B

Target id: 1313

Nomenclature: phosphodiesterase 6B

Abbreviated Name: PDE6B

Family: Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for phosphodiesterase 6B in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 850 4p16.3 PDE6B phosphodiesterase 6B
Mouse - 852 5 53.07 cM Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Rat - - 14 p22 Pde6b phosphodiesterase 6B
Previous and Unofficial Names
phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Database Links
BRENDA
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.1.4.17
Clinically-Relevant Mutations and Pathophysiology
Disease:  Night blindness, congenital stationary, autosomal dominant 2; CSNBAD2
Synonyms: Congenital stationary night blindness [Orphanet: ORPHA215] [Disease Ontology: DOID:0050534]
Disease Ontology: DOID:0050534
OMIM: 163500
Orphanet: ORPHA215
Disease:  Retinitis pigmentosa 40; RP40
Synonyms: Retinitis pigmentosa [Orphanet: ORPHA791] [Disease Ontology: DOID:10584]
Disease Ontology: DOID:10584
OMIM: 613801
Orphanet: ORPHA791

How to cite this page

Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs): phosphodiesterase 6B. Last modified on 10/06/2016. Accessed on 22/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1313.