Puromycin-sensitive aminopeptidase

Target id: 1575

Nomenclature: Puromycin-sensitive aminopeptidase

Family: M1: Aminopeptidase N

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Puromycin-sensitive aminopeptidase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 919 17q12-q21 NPEPPS aminopeptidase puromycin sensitive
Mouse - 920 11 D Npepps aminopeptidase puromycin sensitive
Rat - - 10q31 Npepps aminopeptidase puromycin sensitive
Previous and Unofficial Names
metalloproteinase MP100 | PSA
Database Links
Specialist databases
MEROPS M01.010 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
ANTAQ Hs Inhibition 5.5 pIC50 1
pIC50 5.5 (IC50 2.9x10-6 M) [1]


Show »

1. Kakuta H, Koiso Y, Nagasawa K, Hashimoto Y. (2003) Fluorescent bioprobes for visualization of puromycin-sensitive aminopeptidase in living cells. Bioorg. Med. Chem. Lett., 13 (1): 83-6. [PMID:12467622]

How to cite this page

M1: Aminopeptidase N: Puromycin-sensitive aminopeptidase. Last modified on 28/07/2015. Accessed on 19/09/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1575.