Puromycin-sensitive aminopeptidase

Target id: 1575

Nomenclature: Puromycin-sensitive aminopeptidase

Family: M1: Aminopeptidase N

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Puromycin-sensitive aminopeptidase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 919 17q12-q21 NPEPPS aminopeptidase puromycin sensitive
Mouse - 920 11 D Npepps aminopeptidase puromycin sensitive
Rat - - 10q31 Npepps aminopeptidase puromycin sensitive
Previous and Unofficial Names
metalloproteinase MP100 | PSA
Database Links
Specialist databases
MEROPS M01.010 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.11.14

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
ANTAQ Hs Inhibition 5.5 pIC50 1
pIC50 5.5 (IC50 2.9x10-6 M) [1]

References

Show »

1. Kakuta H, Koiso Y, Nagasawa K, Hashimoto Y. (2003) Fluorescent bioprobes for visualization of puromycin-sensitive aminopeptidase in living cells. Bioorg. Med. Chem. Lett.13 (1): 83-6. [PMID:12467622]

How to cite this page

M1: Aminopeptidase N: Puromycin-sensitive aminopeptidase. Last modified on 28/07/2015. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1575.