X-prolyl aminopeptidase 1

Target id: 1578

Nomenclature: X-prolyl aminopeptidase 1

Family: M24: Methionyl aminopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for X-prolyl aminopeptidase 1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 666 10q25.3 XPNPEP1 X-prolyl aminopeptidase 1
Mouse - 666 19 D2 Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1
Rat - 623 1q55 Xpnpep1 X-prolyl aminopeptidase 1
Previous and Unofficial Names
Aminopeptidase P 1 | aminoacylproline aminopeptidase | cytoplasmic aminopeptidase P | sAmp | soluble aminopeptidase P | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | X-prolyl aminopeptidase (aminopeptidase P) 1
Database Links
Specialist databases
MEROPS M24.009 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
apstatin Hs Inhibition 4.7 pIC50 1
pIC50 4.7 (IC50 2.1x10-5 M) [1]


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1. Maggiora LL, Orawski AT, Simmons WH. (1999) Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme. J. Med. Chem.42 (13): 2394-402. [PMID:10395480]

How to cite this page

M24: Methionyl aminopeptidase: X-prolyl aminopeptidase 1. Last modified on 18/09/2015. Accessed on 19/03/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1578.