Top ▲

X-prolyl aminopeptidase 1

Click here for help

Target not currently curated in GtoImmuPdb

Target id: 1578

Nomenclature: X-prolyl aminopeptidase 1

Family: M24: Methionyl aminopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 623 10q25.1 XPNPEP1 X-prolyl aminopeptidase 1
Mouse - 623 19 D2 Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Rat - 623 1q55 Xpnpep1 X-prolyl aminopeptidase 1
Previous and Unofficial Names Click here for help
Aminopeptidase P 1 | aminoacylproline aminopeptidase | cytoplasmic aminopeptidase P | sAmp | soluble aminopeptidase P | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | X-prolyl aminopeptidase (aminopeptidase P) 1
Database Links Click here for help
Specialist databases
MEROPS M24.009 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
apstatin Small molecule or natural product Click here for species-specific activity table Hs Inhibition 4.7 pIC50 1
pIC50 4.7 (IC50 2.1x10-5 M) [1]


Show »

1. Maggiora LL, Orawski AT, Simmons WH. (1999) Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme. J Med Chem, 42 (13): 2394-402. [PMID:10395480]

How to cite this page

M24: Methionyl aminopeptidase: X-prolyl aminopeptidase 1. Last modified on 18/09/2015. Accessed on 27/01/2023. IUPHAR/BPS Guide to PHARMACOLOGY,