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Targets
- G protein-coupled receptors
- Ion channels
- Nuclear hormone receptors
- Kinases
- Catalytic receptors
- Transporters
- Enzymes
- Other protein targets
Ligands
- Approved drugs
- Synthetic organics
- Metabolites
- Natural products
- Endogenous peptides
- Other peptides
- Inorganics
- Antibodies
- Labelled ligands
Resources
Recent Twitter activity
What's new to Guide to PHARMACOLOGY
New database version 2019.5 - released 13th November 2019
- The IUPHAR/MMV Guide to Malaria Pharmacology now includes direct links from targets to PlasmoDB
- 5 novel GPR55 peptide ligands as reported by Foster et al. (2019): Ligand IDs 10539-10543
- A new group of ligands, PROTACs and molecular glues, has been curated, with targets including kinases, tau protein and the chromatin modifying proteins BRD4, BRD9 and TRIM24
- Button on ligand list pages for downloading specific sets of ligands
- The 39th Congresso Nazionale SIF (Florence, Nov 20-23)
- The Glasgow-Edinburgh Malaria Meeting (Edinburgh, Dec 11)
- BPS Pharmacology 2019 - Workshop: Guide to Immunopharmacology (Edinburgh, Dec 15-17)
Upcoming presentations at:
Latest News and Hot Topics in Pharmacology
GtoMPdb
IUPHAR/MMV Guide to Malaria Pharmacology
Visit the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY portal
Launched in September 2019 to provide optimised access to GtoPdb data for the malaria research community
The Concise Guide to PHARMACOLOGY 2019/20
Recent Publications
IUPHAR review article on two-pore domain potassium channels
Gada K & Plant LD (2019) Br J Pharmacol. 176(2):256-266. doi: 10.1111/bph.14518. 
IUPHAR review article on the pharmacology of calcitonin/CGRP family of peptides
Hay DL, Garelja ML, Poyner DR, et al. (2018) Br J Pharmacol. 175(1):3-17. doi: 10.1111/bph.14075.
IUPHAR review article on Structure and Pharmacology of the Apelin Receptor
Read C, Nyimanu D, Williams TL, Huggins DJ, Sulentic P, Macrae RGC, Yang P, Glen RC, Maguire JJ and Davenport AP (2019) Pharmacol Rev. 71: 764-502.
IUPHAR review article on GABAA Receptor Subtype- and Function-selective Ligands
Sieghart W & Savić MM. (2018) Pharmacol Rev. 70: 836-878.
Pharmacology Education
The IUPHAR Pharmacology Education Project is being developed by IUPHAR with support from ASPET as a learning resource for pharmacology and clinical pharmacology.
synPHARM
SynPharm is a database of ligand-responsive protein sequences, derived from interactions from the Guide to PHARMACOLOGY and using data from the Protein Data Bank.
Pharmacology 2019
The British Pharmacological Society's flagship annual meeting attracts over 1,200 scientists each year from across the world.
15-17 Dec 2019, Edinburgh, UK
Includes: Workshop: Guide to Immunopharmacology - How to Navigate and Use the Database
Sunday 15th Dec, 15:00-16:30
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