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Targets
- G protein-coupled receptors
- Ion channels
- Nuclear hormone receptors
- Kinases
- Catalytic receptors
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- Enzymes
- Other protein targets
Ligands
- Approved drugs
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Resources
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What's new to Guide to PHARMACOLOGY
Latest database release, version 2019.4 released 18th September 2019
- Release 2019.4 is the fourth release of the, please read full release details in our blog post
- We are pleased to announce the first full-release of the IUPHAR/MMV Guide to Malaria Pharmacology
- The Antimalarial targets family and the Antimalarial ligands family have been updated, giving a total of 30 P. falciparum (3D7) targets and 72 ligands tagged as antimalarial in the database
- New ligand category listing compounds included in the World Health Organization (WHO) Model List of Essential Medicines
- Addition of content statistics on immunopharmacology
Latest News and Hot Topics in Pharmacology
GtoMPdb
IUPHAR/MMV Guide to Malaria Pharmacology
Visit the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY portal
Launched in September 2019 to provide optimised access to GtoPdb data for the malaria research community
The Concise Guide to PHARMACOLOGY 2017/18
A FREE publication snapshot created from the database summary pages.
Please see the 5 minute introductory video on the Concise Guide:
Recent Publications
IUPHAR review article on two-pore domain potassium channels
Gada K & Plant LD (2019) Br J Pharmacol. 176(2):256-266. doi: 10.1111/bph.14518. 
IUPHAR review article on the pharmacology of calcitonin/CGRP family of peptides
Hay DL, Garelja ML, Poyner DR, et al. (2018) Br J Pharmacol. 175(1):3-17. doi: 10.1111/bph.14075.
IUPHAR review article on Structure and Pharmacology of the Apelin Receptor
Read C, Nyimanu D, Williams TL, Huggins DJ, Sulentic P, Macrae RGC, Yang P, Glen RC, Maguire JJ and Davenport AP (2019) Pharmacol Rev. 71: 764-502.
IUPHAR review article on GABAA Receptor Subtype- and Function-selective Ligands
Sieghart W & Savić MM. (2018) Pharmacol Rev. 70: 836-878.
Pharmacology Education
The IUPHAR Pharmacology Education Project is being developed by IUPHAR with support from ASPET as a learning resource for pharmacology and clinical pharmacology.
synPHARM
SynPharm is a database of ligand-responsive protein sequences, derived from interactions from the Guide to PHARMACOLOGY and using data from the Protein Data Bank.
Pharmacology 2019
The British Pharmacological Society's flagship annual meeting attracts over 1,200 scientists each year from across the world.
15-17 Dec 2019, Edinburgh, UK
Abstract submission: closes 13th Sep
Register now: Early bird deadline is 18th Oct
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