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IUPHAR/Servier Fibrosis Symposium
NEW! View and read the scientific presentations and report from the IUPHAR/Servier Fibrosis Symposium, held in November 2020.
What's new to Guide to PHARMACOLOGY
Coronavirus (Covid-19) - view our information page
Database version 2020.5 (12 Nov 2020) - read release details in our blog
Our latest release includes:
- Curated some entities from the WHO list of COVID-related therapeutics (October 20): alunacedase alfa, eclitasertib, enpatoran, molnupiravir, nezulcitinib, subasumstat
- New family added: SLC66 Lysosomal amino acid transporters
- New immuno target added: cyclic GMP-AMP synthase (cGAS)
- Total curated Anti-malarial ligands now stands at 100!
Read our latest Database Report (Nov 2020) - download/view PDF
GtoPdb at BPS Pharmacology 2020. See our posters and presentations!
Latest News and Hot Topics in Pharmacology
Pharmacology of COVID-19
Themed issue in BJP
This themed issue includes IUPHAR Review 29: A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development, which made the cover of the issue.
The Concise Guide to PHARMACOLOGY 2019/20
Recent Publications
A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development. IUPHAR Review 29
Alexander SPH, Armstrong J, Davenport AP, Davies JA, Faccenda E, Harding SD, Levi-Schaffer F, Maguire JJ, Pawson AJ, Southan C, Spedding MJ (2020) Br J Pharmacol. 177(21):4942-4966. doi: 10.1111/bph.15094. 
Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28
Mariotti FR, Quatrini L, Munari E, Vacca P, Tumino N, Pietra G, Mingari MC, Moretta L (2020) Br J Pharmacol. 177(13):2889-2903. doi: 10.1111/bph.15081.
IUPHAR Review CXI: Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors
Gregory KJ, Goudet C (2021) Pharmacol Rev. 73: 521-569.
IUPHAR Review CX: Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, Claeysen S, Cunningham KA, Fone KC, Gershon M, Di Giovanni G, Goodfellow NM, Halberstadt AL, Hartley RM, Hassaine G, Herrick-Davis K, Hovius R, Lacivita E, Lambe EK, Leopoldo M, Levy FO, Lummis SCR, Marin P, Maroteaux L, McCreary AC, Nelson DL, Neumaier JF, Newman-Tancredi A, Nury H, Roberts A, Roth BL, Roumier A, Sanger GJ, Teitler M, Sharp T, Villalón CM, Vogel H, Watts SW, Hoyer D (2021) Pharmacol Rev. 73: 310-520.
Pharmacology Education
The IUPHAR Pharmacology Education Project is being developed by IUPHAR with support from ASPET as a learning resource for pharmacology and clinical pharmacology.
synPHARM
SynPharm is a database of ligand-responsive protein sequences, derived from interactions from the Guide to PHARMACOLOGY and using data from the Protein Data Bank.
Coronavirus
Our coronavirus information page has details of pharmcological strategies aimed at mitigating against COVID-19. The page also contains links to other useful resources and publications.
Please see our pre-print manuscript on "A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development"
Celebrating >20 years of Servier support
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