Useful links

Databases of drugs and drug targets

GPCR databases

VGIC and LGIC databases

Nuclear Receptor databases

Enzyme databases

  • EBI Enzyme Portal
  • ExplorEnz: A resource providing access to the data of the International Union of Biochemistry and Molecular Biology (IUBMB) Enzyme Nomenclature List, and which maintains the IUPAC standard formatting of chemical names.
  • PhosphoSitePlus: An expert curated database providing access to information and tools useful to the study of in-vivo post-translational modification of proteins of the kinome.

Transporter databases

Antibody resources

Gene/protein databases

  • GeneCards: A searchable, integrated, database that provides concise genomic related information, on all known and predicted human genes. Includes MalaCards, the human disease database. Note that GeneCards is free for academic and non-profit use but commercial users require a license.
  • InterPro: integrates protein information from several allied databases into a single searchable resource providing protein family classification information, functional domain prediction and identification of other important sites on proteins.
  • HomoloGene: An automated system for constructing putative homology groups from the genomes of a wide range of eukaryotic species.
  • HUGO Gene Nomenclature Committee (HGNC)
  • KEGG: Kyoto Encyclopedia of Genes and Genomes
  • neXtProt: a human protein-centric knowledgebase providing access to a range of high-quality datasets with tools to mine them.
  • Pfam: a collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs)
  • Protein Ontology: an ontological representation of protein-related entities by explicitly defining them and showing the relationships between them.
  • Treefam: a database of animal gene trees, encompassing inferred phylogenetic trees, predicted orthologues/parologues and the evolutionary history of genes.
  • UniGene: a database of the transcriptome providing information on protein similarities, gene expression, cDNA clones, and genomic location.
  • UniProt: resource for protein sequence and functional information

Metabolite databases

Other relevant resources

Journals

Other useful links

UoE Teaching Materials (Jan 2019)