Interleukin-2 receptor subunit β

Target id: 1696

Nomenclature: Interleukin-2 receptor subunit β

Family: IL-2 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin-2 receptor subunit β has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-2 receptor
Interleukin-15 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 551 22q12.3 IL2RB interleukin 2 receptor subunit beta
Mouse 1 539 Il2rb interleukin 2 receptor
Rat 1 537 Il2rb interleukin 2 receptor subunit beta
Previous and Unofficial Names
CD122 | IL15RB | interleukin 15 receptor, beta | high affinity IL-2 receptor subunit beta | IL-2R subunit beta | IL-15 receptor beta chain | IL-2/15Rbeta
Database Links
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
IL2RB is a ligand binding component of the IL-2R and is required to elevate ligand affinity. It also a component of the IL-15R.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  interleukin-2 receptor activity (GO:0004911) IDA
cytokine-mediated signaling pathway (GO:0019221) IDA
References: 

How to cite this page

IL-2 receptor family: Interleukin-2 receptor subunit β. Last modified on 28/03/2017. Accessed on 12/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1696.