Oncostatin M-specific receptor, β subunit | IL-6 receptor family | IUPHAR/BPS Guide to PHARMACOLOGY

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Oncostatin M-specific receptor, β subunit

Target id: 1714

Nomenclature: Oncostatin M-specific receptor, β subunit

Family: IL-6 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Oncostatin M-specific receptor, β subunit has curated data in GtoImmuPdb

Quaternary Structure: Complexes
Interleukin-31 receptor
Oncostatin-M receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - OSMR oncostatin M receptor
Mouse - - Osmr oncostatin M receptor
Rat - - Osmr oncostatin M receptor
Previous and Unofficial Names
IL-31 receptor subunit beta | IL-31RB | interleukin-31 receptor subunit beta | oncostatin M receptor | OSMRB
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Oncostatin M-specific receptor, β subunit (OSMR) is a component of two functional heterodimeric receptor complexes:
1. OSMR+ interleukin-6 receptor, β subunit (IL6ST) forms the receptor for oncostatin M
2. OSMR+ interleukin-31 receptor, α subunit forms the receptor for IL-31
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 1 GO processes
GO:0002675 positive regulation of acute inflammatory response IC
Immuno Process:  Immune regulation
GO Annotations:  Associated to 1 GO processes
GO:0002675 positive regulation of acute inflammatory response IC
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 3 GO processes
GO:0034097 response to cytokine IDA
GO:0038165 oncostatin-M-mediated signaling pathway IMP
click arrow to show/hide IEA associations
GO:0004896 cytokine receptor activity IEA

How to cite this page

IL-6 receptor family: Oncostatin M-specific receptor, β subunit. Last modified on 07/04/2017. Accessed on 11/12/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1714.