Oncostatin M-specific receptor, β subunit

Target id: 1714

Nomenclature: Oncostatin M-specific receptor, β subunit

Family: IL-6 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Oncostatin M-specific receptor, β subunit has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-31 receptor
Oncostatin-M receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - OSMR oncostatin M receptor
Mouse - - Osmr oncostatin M receptor
Rat - - Osmr oncostatin M receptor
Previous and Unofficial Names
IL-31 receptor subunit beta | IL-31RB | interleukin-31 receptor subunit beta | oncostatin M receptor | OSMRB
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Oncostatin M-specific receptor, β subunit (OSMR) is a component of two functional heterodimeric receptor complexes:
1. OSMR+ interleukin-6 receptor, β subunit (IL6ST) forms the receptor for oncostatin M
2. OSMR+ interleukin-31 receptor, α subunit forms the receptor for IL-31
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of acute inflammatory response (GO:0002675) IC
References: 
Immuno Process:  Immune regulation
Immuno Process ID:  6
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of acute inflammatory response (GO:0002675) IC
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  cytokine receptor activity (GO:0004896) IEA
response to cytokine (GO:0034097) IDA
oncostatin-M-mediated signaling pathway (GO:0038165) IMP
References: 

How to cite this page

IL-6 receptor family: Oncostatin M-specific receptor, β subunit. Last modified on 07/04/2017. Accessed on 16/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1714.