acylaminoacyl-peptide hydrolase

Target id: 2328

Nomenclature: acylaminoacyl-peptide hydrolase

Family: S9: Prolyl oligopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for acylaminoacyl-peptide hydrolase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 732 3p21 APEH acylaminoacyl-peptide hydrolase
Mouse - 732 9 F2 Apeh acylpeptide hydrolase
Rat - 732 8q32 Apeh acylaminoacyl-peptide hydrolase
Previous and Unofficial Names
AARE | acyl-peptide hydrolase | APH | acylamino-acid-releasing enzyme
Database Links
Specialist databases
MEROPS S09.004 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
ARI-3099 Hs Inhibition 7.0 pIC50 1
pIC50 7.0 (IC50 1.04x10-7 M) [1]
Description: Substrate (Ac-Ala-AMC) assay.


Show »

1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat. Chem. Biol.10 (8): 656-63. [PMID:24997602]

How to cite this page

S9: Prolyl oligopeptidase: acylaminoacyl-peptide hydrolase. Last modified on 20/07/2015. Accessed on 24/02/2018. IUPHAR/BPS Guide to PHARMACOLOGY,