Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	729	3p21.1	BAP1	BRCA1 associated deubiquitinase 1
Mouse	-	728	14 B	Bap1	Brca1 associated protein 1
Rat	-	727	16p16	Bap1	BRCA1 associated deubiquitinase 1

Previous and Unofficial Names

BRCA1 associated protein 1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) | hucep-6 | ubiquitin C-terminal hydrolase X4 | UCHL2 | uch-x4

Database Links
Specialist databases
MEROPS	C12.004 (Hs)
Other databases
Alphafold	Q92560 (Hs), Q99PU7 (Mm), D3ZHS6 (Rn)
BRENDA	3.4.19.12
CATH/Gene3D	3.40.532.10
ChEMBL Target	CHEMBL1293314 (Hs)
Ensembl Gene	ENSG00000163930 (Hs), ENSMUSG00000021901 (Mm), ENSRNOG00000019097 (Rn)
Entrez Gene	8314 (Hs), 104416 (Mm), 306257 (Rn)
Human Protein Atlas	ENSG00000163930 (Hs)
KEGG Enzyme	3.4.19.12
KEGG Gene	hsa:8314 (Hs), mmu:104416 (Mm), rno:306257 (Rn)
OMIM	603089 (Hs)
Orphanet	ORPHA289543 (Hs)
Pharos	Q92560 (Hs)
RefSeq Nucleotide	NM_004656 (Hs), NM_027088 (Mm), NM_001107292 (Rn)
RefSeq Protein	NP_004647 (Hs), NP_081364 (Mm), NP_001100762 (Rn)
UniProtKB	Q92560 (Hs), Q99PU7 (Mm), D3ZHS6 (Rn)
Wikipedia	BAP1 (Hs)

Enzyme Reaction
EC Number: 3.4.19.12

Clinically-Relevant Mutations and Pathophysiology
Disease:  Malignant mesothelioma Disease Ontology: DOID:1790 OMIM: 156240
Disease:  Tumor predisposition syndrome Synonyms: BAP1-related tumor predisposition syndrome [Orphanet: ORPHA289539] OMIM: 614327 Orphanet: ORPHA289539