tryptase gamma 1

Target id: 2425

Nomenclature: tryptase gamma 1

Family: S1: Chymotrypsin

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for tryptase gamma 1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 321 16p13.3 TPSG1 tryptase gamma 1
Mouse - 311 17 A3.3 Tpsg1 tryptase gamma 1
Rat - 311 10q12 Tpsg1 tryptase gamma 1
Previous and Unofficial Names
tryptase gamma I | Prss31 | Tmt | transmembrane tryptase | tryptase gamma II
Database Links
Specialist databases
MEROPS S01.028 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.21.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
WX-UK1 ? Inhibition 5.2 pKi 1
pKi 5.2 (Ki 6.3x10-6 M) [1]

References

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1. Stürzebecher J, Vieweg H, Steinmetzer T, Schweinitz A, Stubbs MT, Renatus M, Wikström P. (1999) 3-Amidinophenylalanine-based inhibitors of urokinase. Bioorg. Med. Chem. Lett.9 (21): 3147-52. [PMID:10560742]

How to cite this page

S1: Chymotrypsin: tryptase gamma 1. Last modified on 29/07/2015. Accessed on 19/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2425.