ubiquitin specific peptidase 5

Target id: 2431

Nomenclature: ubiquitin specific peptidase 5

Family: C19: Ubiquitin-specific protease

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for ubiquitin specific peptidase 5 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 858 12p13 USP5 ubiquitin specific peptidase 5
Mouse - 858 6 F2 Usp5 ubiquitin specific peptidase 5 (isopeptidase T)
Rat - 858 4q42 Usp5 ubiquitin specific peptidase 5
Previous and Unofficial Names
deubiquitinating enzyme 5 | IsoT | ubiquitin carboxy terminal hydrolase T | ubiquitin carboxyl-terminal hydrolase 5 | ubiquitin specific protease 5 | ubiquitin thioesterase 5 | ubiquitin thiolesterase 5 | Ucht | ubiquitin specific peptidase 5 (isopeptidase T)
Database Links
Specialist databases
MEROPS C19.001 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
vialinin A Hs Inhibition 5.4 pKi 1
pKi 5.4 (Ki 4x10-6 M) [1]


Show »

1. Okada K, Ye YQ, Taniguchi K, Yoshida A, Akiyama T, Yoshioka Y, Onose J, Koshino H, Takahashi S, Yajima A et al.. (2013) Vialinin A is a ubiquitin-specific peptidase inhibitor. Bioorg. Med. Chem. Lett.23 (15): 4328-31. [PMID:23791076]

How to cite this page

C19: Ubiquitin-specific protease: ubiquitin specific peptidase 5. Last modified on 28/07/2015. Accessed on 17/02/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2431.