acetyl-CoA acetyltransferase 2 | Lanosterol biosynthesis pathway | IUPHAR/BPS Guide to PHARMACOLOGY

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acetyl-CoA acetyltransferase 2

Target id: 2436

Nomenclature: acetyl-CoA acetyltransferase 2

Family: Lanosterol biosynthesis pathway

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for acetyl-CoA acetyltransferase 2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 397 6q25.3-q26 ACAT2 acetyl-CoA acetyltransferase 2 1
Mouse - 397 17 A2-A3 Acat2 acetyl-Coenzyme A acetyltransferase 2
Rat - 397 1q11 Acat2 acetyl-CoA acetyltransferase 2
Previous and Unofficial Names
Acat3 | Acetyl-CoA acetyltransferase, cytosolic | Cytosolic acetoacetyl-CoA thiolase | acetoacetyl Coenzyme A thiolase | acetyl-Coenzyme A acetyltransferase 3
Database Links
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number: 2acetyl CoA = acetoacetyl CoA + coenzyme A
Clinically-Relevant Mutations and Pathophysiology
Disease:  Acetyl-CoA acetyltransferase-2 deficiency; ACAT2D
OMIM: 614055


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1. Masuno M, Fukao T, Song XQ, Yamaguchi S, Orii T, Kondo N, Imaizumi K, Kuroki Y. (1996) Assignment of the human cytosolic acetoacetyl-coenzyme A thiolase (ACAT2) gene to chromosome 6q25.3-q26. Genomics, 36 (1): 217-8. [PMID:8812443]


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How to cite this page

Helen E. Benson.
Lanosterol biosynthesis pathway: acetyl-CoA acetyltransferase 2. Last modified on 03/07/2014. Accessed on 20/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY,