Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	517	4q12	PPAT	phosphoribosyl pyrophosphate amidotransferase
Mouse	-	517	5 C3	Ppat	phosphoribosyl pyrophosphate amidotransferase
Rat	-	517	14p11	Ppat	phosphoribosyl pyrophosphate amidotransferase

Previous and Unofficial Names

PRAT | glutamine phosphoribosylpyrophosphate amidotransferase | GPAT | amidophosphoribosyltransferase

Database Links
Specialist databases
MEROPS	C44.001 (Hs)
Other databases
BRENDA	2.4.2.14
CATH/Gene3D	3.60.20.10
Ensembl Gene	ENSG00000128059 (Hs), ENSMUSG00000029246 (Mm), ENSRNOG00000002128 (Rn)
Entrez Gene	5471 (Hs), 231327 (Mm), 117544 (Rn)
Human Protein Atlas	ENSG00000128059 (Hs)
KEGG Enzyme	2.4.2.14
KEGG Gene	hsa:5471 (Hs), mmu:231327 (Mm), rno:117544 (Rn)
OMIM	172450 (Hs)
RefSeq Nucleotide	NM_002703 (Hs), NM_172146 (Mm), NM_057198 (Rn)
RefSeq Protein	NP_002694 (Hs), NP_742158 (Mm), NP_476546 (Rn)
UniProtKB	Q06203 (Hs), P35433 (Rn)
Wikipedia	PPAT (Hs)

Enzyme Reaction
EC Number: 2.4.2.14

General Comments
Confirmed enzymatic activity of PPAT is primarily as a glutamine amidotransferase. InterPro does not predict protease domain matches but does identify protease-like fold structure (see also the MEROPS cross-link in the Database Links table above).