phosphoribosyl pyrophosphate amidotransferase
Target id: 2761
Nomenclature: phosphoribosyl pyrophosphate amidotransferase
Family: C44: Phosphoribosyl pyrophosphate amidotransferase
Annotation status:
Awaiting annotation/under development. Please contact us if you can help with annotation.
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GtoImmuPdb view: OFF : Currently no data for phosphoribosyl pyrophosphate amidotransferase in GtoImmuPdb
Contents:
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 517 | 4q12 | PPAT | phosphoribosyl pyrophosphate amidotransferase | |
| Mouse | - | 517 | 5 C3 | Ppat | phosphoribosyl pyrophosphate amidotransferase | |
| Rat | - | 517 | 14p11 | Ppat | phosphoribosyl pyrophosphate amidotransferase | |
| Previous and Unofficial Names |
| PRAT | glutamine phosphoribosylpyrophosphate amidotransferase | GPAT | amidophosphoribosyltransferase |
| Database Links |
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| Specialist databases | |
| MEROPS | C44.001 (Hs) |
| Other databases | |
| BRENDA | 2.4.2.14 |
| CATH/Gene3D | 3.60.20.10 |
| Ensembl Gene | ENSG00000128059 (Hs), ENSMUSG00000029246 (Mm), ENSRNOG00000002128 (Rn) |
| Entrez Gene | 5471 (Hs), 231327 (Mm), 117544 (Rn) |
| Human Protein Atlas | ENSG00000128059 (Hs) |
| KEGG Enzyme | 2.4.2.14 |
| KEGG Gene | hsa:5471 (Hs), mmu:231327 (Mm), rno:117544 (Rn) |
| OMIM | 172450 (Hs) |
| RefSeq Nucleotide | NM_002703 (Hs), NM_172146 (Mm), NM_057198 (Rn) |
| RefSeq Protein | NP_002694 (Hs), NP_742158 (Mm), NP_476546 (Rn) |
| UniProtKB | Q06203 (Hs), P35433 (Rn) |
| Wikipedia | PPAT (Hs) |
| Enzyme Reaction |
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| General Comments |
| Confirmed enzymatic activity of PPAT is primarily as a glutamine amidotransferase. InterPro does not predict protease domain matches but does identify protease-like fold structure (see also the MEROPS cross-link in the Database Links table above). |
How to cite this page
C44: Phosphoribosyl pyrophosphate amidotransferase: phosphoribosyl pyrophosphate amidotransferase. Last modified on 14/02/2017. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2761.
