phosphoribosyl pyrophosphate amidotransferase | C44: Phosphoribosyl pyrophosphate amidotransferase | IUPHAR/BPS Guide to PHARMACOLOGY

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phosphoribosyl pyrophosphate amidotransferase

Target not currently curated in GtoImmuPdb

Target id: 2761

Nomenclature: phosphoribosyl pyrophosphate amidotransferase

Family: C44: Phosphoribosyl pyrophosphate amidotransferase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 517 4q12 PPAT phosphoribosyl pyrophosphate amidotransferase
Mouse - 517 5 C3 Ppat phosphoribosyl pyrophosphate amidotransferase
Rat - 517 14p11 Ppat phosphoribosyl pyrophosphate amidotransferase
Previous and Unofficial Names
PRAT | glutamine phosphoribosylpyrophosphate amidotransferase | GPAT | amidophosphoribosyltransferase
Database Links
Specialist databases
MEROPS C44.001 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:
General Comments
Confirmed enzymatic activity of PPAT is primarily as a glutamine amidotransferase. InterPro does not predict protease domain matches but does identify protease-like fold structure (see also the MEROPS cross-link in the Database Links table above).

How to cite this page

C44: Phosphoribosyl pyrophosphate amidotransferase: phosphoribosyl pyrophosphate amidotransferase. Last modified on 14/02/2017. Accessed on 10/07/2020. IUPHAR/BPS Guide to PHARMACOLOGY,