phosphoribosyl pyrophosphate amidotransferase

Target id: 2761

Nomenclature: phosphoribosyl pyrophosphate amidotransferase

Family: C44: Phosphoribosyl pyrophosphate amidotransferase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for phosphoribosyl pyrophosphate amidotransferase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 517 4q12 PPAT phosphoribosyl pyrophosphate amidotransferase
Mouse - 517 5 C3 Ppat phosphoribosyl pyrophosphate amidotransferase
Rat - 517 14p11 Ppat phosphoribosyl pyrophosphate amidotransferase
Previous and Unofficial Names
PRAT | glutamine phosphoribosylpyrophosphate amidotransferase | GPAT | amidophosphoribosyltransferase
Database Links
Specialist databases
MEROPS C44.001 (Hs)
Other databases
BRENDA
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 2.4.2.14
General Comments
Confirmed enzymatic activity of PPAT is primarily as a glutamine amidotransferase. InterPro does not predict protease domain matches but does identify protease-like fold structure (see also the MEROPS cross-link in the Database Links table above).

How to cite this page

C44: Phosphoribosyl pyrophosphate amidotransferase: phosphoribosyl pyrophosphate amidotransferase. Last modified on 14/02/2017. Accessed on 18/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2761.