asparaginase

Target id: 2762

Nomenclature: asparaginase

Family: 3.1.1.- Carboxylic Ester Hydrolases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for asparaginase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 573 14q32.33 ASPG asparaginase
Mouse - 564 12 F1 Aspg asparaginase
Rat - 564 6q32 Aspg asparaginase
Previous and Unofficial Names
60 kDa lysophospholipase | GPA/WT | LPP60 | asparaginase homolog (S. cerevisiae)
Database Links
BRENDA
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.1.1.5
EC Number: 3.1.1.47
EC Number: 3.5.1.1
General Comments
This protein has multiple functions. It acts as a lysophospholipase, a transacylase, a platelet-activating factor (PAF) acetylhydrolase and an L-asparaginase. L-asparaginase catalyses the deamination of asparagine to aspartic acid and a single ammonium ion. This action decreases circulating free asparagine in plasma.

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: asparaginase. Last modified on 13/08/2015. Accessed on 21/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2762.