Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	702	19q13.2	CEACAM5	CEA cell adhesion molecule 5

Previous and Unofficial Names

CEA | carcinoembryonic antigen-related cell adhesion molecule 5 | carcinoembryonic antigen related cell adhesion molecule 5

Database Links
Alphafold	P06731 (Hs)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL3712881 (Hs)
Ensembl Gene	ENSG00000105388 (Hs)
Entrez Gene	1048 (Hs)
Human Protein Atlas	ENSG00000105388 (Hs)
KEGG Gene	hsa:1048 (Hs)
OMIM	114890 (Hs)
Pharos	P06731 (Hs)
RefSeq Nucleotide	NM_004363 (Hs)
RefSeq Protein	NP_004354 (Hs)
UniProtKB	P06731 (Hs)
Wikipedia	CEACAM5 (Hs)

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Antibodies
Key to terms and symbols		Click column headers to sort
Antibody Sp. Action Value Parameter Reference labetuzumab Hs Binding - - ⤷ labetuzumab govitecan Hs Binding - - ⤷

Immunopharmacology Comments

CD66e is included in GtoImmuPdb because of its role in pathogen recognition.

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Chemotaxis & migration

General Comments
CD66e (CEACAM5) is an epithelially expressed molecule required for cell adhesion, cellular migration, pathogen binding and activation of signaling pathways. This protein contains an immunoglobulin (Ig)-like domain that resembles the antibody variable domain, that has been coined the 'V-set domain'. The genes for all human V-set domain containing proteins are listed in HGNC gene group 590.