Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	702	19q13.2	CEACAM5	CEA cell adhesion molecule 5

Previous and Unofficial Names

CEA | carcinoembryonic antigen-related cell adhesion molecule 5 | carcinoembryonic antigen related cell adhesion molecule 5

Database Links
Alphafold	P06731 (Hs)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL3712881 (Hs)
Ensembl Gene	ENSG00000105388 (Hs)
Entrez Gene	1048 (Hs)
Human Protein Atlas	ENSG00000105388 (Hs)
KEGG Gene	hsa:1048 (Hs)
OMIM	114890 (Hs)
Pharos	P06731 (Hs)
RefSeq Nucleotide	NM_004363 (Hs)
RefSeq Protein	NP_004354 (Hs)
UniProtKB	P06731 (Hs)
Wikipedia	CEACAM5 (Hs)

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Antibodies
Key to terms and symbols		Click column headers to sort
Antibody Sp. Action Value Parameter Reference labetuzumab Hs Binding - - ⤷ labetuzumab govitecan Hs Binding - - ⤷

Immunopharmacology Comments

CD66e is included in GtoImmuPdb because of its role in pathogen recognition.

General Comments
CD66e (CEACAM5) is an epithelially expressed molecule required for cell adhesion, cellular migration, pathogen binding and activation of signaling pathways. This protein contains an immunoglobulin (Ig)-like domain that resembles the antibody variable domain, that has been coined the 'V-set domain'. The genes for all human V-set domain containing proteins are listed in HGNC gene group 590.