prolyl endopeptidase like

Target id: 2870

Nomenclature: prolyl endopeptidase like

Family: S9: Prolyl oligopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for prolyl endopeptidase like in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 727 2p22.1 PREPL prolyl endopeptidase like
Mouse - 725 17 E4 Prepl prolyl endopeptidase-like
Rat - 638 6q12 Prepl prolyl endopeptidase-like
Previous and Unofficial Names
prolyl endopeptidase-like
Database Links
Specialist databases
MEROPS S09.015 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 8 [PMID: 21692504] Mm Inhibition 5.2 pIC50 1
pIC50 5.2 (IC50 6x10-6 M) [1]
Description: In a substrate free assay.


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1. Lone AM, Bachovchin DA, Westwood DB, Speers AE, Spicer TP, Fernandez-Vega V, Chase P, Hodder PS, Rosen H, Cravatt BF et al.. (2011) A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors. J. Am. Chem. Soc.133 (30): 11665-74. [PMID:21692504]

How to cite this page

S9: Prolyl oligopeptidase: prolyl endopeptidase like. Last modified on 27/02/2018. Accessed on 23/04/2018. IUPHAR/BPS Guide to PHARMACOLOGY,