Fc fragment of IgE receptor Ig

Target id: 2934

Nomenclature: Fc fragment of IgE receptor Ig

Abbreviated Name: FCεR1γ

Family: Fc epsilon receptors

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Fc fragment of IgE receptor Ig has curated GtoImmuPdb data

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 86 1q23.3 FCER1G Fc fragment of IgE receptor Ig
Mouse 1 86 1 H3; 1 79.23 cM Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide
Rat 1 86 13q24 Fcer1g Fc fragment of IgE receptor Ig
Previous and Unofficial Names
Fc epsilon receptor Ig | high affinity I, receptor for Fc fragment of IgE | Ly-50
Database Links
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of type IIa hypersensitivity (GO:0001798) IEA
positive regulation of type III hypersensitivity (GO:0001805) IEA
positive regulation of type I hypersensitivity (GO:0001812) IEA
stimulatory C-type lectin receptor signaling pathway (GO:0002223) TAS
neutrophil activation involved in immune response (GO:0002283) IBA
T cell differentiation involved in immune response (GO:0002292) IBA
serotonin secretion by platelet (GO:0002554) IEA
phagocytosis, engulfment (GO:0006911) IEA
neutrophil chemotaxis (GO:0030593) IBA
positive regulation of mast cell degranulation (GO:0043306) IEA
neutrophil degranulation (GO:0043312) TAS
innate immune response (GO:0045087) IBA
mast cell activation (GO:0045576) IEA
positive regulation of phagocytosis (GO:0050766) IBA
leukocyte migration (GO:0050900) TAS
References: 
Immuno Process:  Antigen presentation
Immuno Process ID:  3
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  phagocytosis, engulfment (GO:0006911) IEA
antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886) IBA
receptor internalization (GO:0031623) ISS
antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) IBA
positive regulation of phagocytosis (GO:0050766) IBA
References: 
Immuno Process:  T cell (activation)
Immuno Process ID:  4
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of type IIa hypersensitivity (GO:0001798) IEA
positive regulation of type III hypersensitivity (GO:0001805) IEA
positive regulation of type I hypersensitivity (GO:0001812) IEA
T cell differentiation involved in immune response (GO:0002292) IBA
immunoglobulin mediated immune response (GO:0016064) IBA
References: 
Immuno Process:  B cell (activation)
Immuno Process ID:  5
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of type IIa hypersensitivity (GO:0001798) IEA
positive regulation of type III hypersensitivity (GO:0001805) IEA
positive regulation of type I hypersensitivity (GO:0001812) IEA
immunoglobulin mediated immune response (GO:0016064) IBA
References: 
Immuno Process:  Immune regulation
Immuno Process ID:  6
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  positive regulation of type IIa hypersensitivity (GO:0001798) IEA
positive regulation of type III hypersensitivity (GO:0001805) IEA
positive regulation of type I hypersensitivity (GO:0001812) IEA
stimulatory C-type lectin receptor signaling pathway (GO:0002223) TAS
Fc receptor mediated stimulatory signaling pathway (GO:0002431) IBA
IgE receptor activity (GO:0019767) IBA
positive regulation of mast cell cytokine production (GO:0032765) IEA
negative regulation of mast cell apoptotic process (GO:0033026) IEA
Fc-gamma receptor signaling pathway (GO:0038094) IBA
Fc-epsilon receptor signaling pathway (GO:0038095) TAS
positive regulation of mast cell degranulation (GO:0043306) IEA
References: 
Immuno Process:  Immune system development
Immuno Process ID:  8
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  T cell differentiation involved in immune response (GO:0002292) IBA
References: 
Immuno Process:  Chemotaxis & migration
Immuno Process ID:  10
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  neutrophil chemotaxis (GO:0030593) IBA
leukocyte migration (GO:0050900) TAS
References: 
Immuno Process:  Cellular signalling
Immuno Process ID:  11
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  stimulatory C-type lectin receptor signaling pathway (GO:0002223) TAS
neutrophil activation involved in immune response (GO:0002283) IBA
T cell differentiation involved in immune response (GO:0002292) IBA
Fc receptor mediated stimulatory signaling pathway (GO:0002431) IBA
IgE receptor activity (GO:0019767) IBA
Fc-gamma receptor signaling pathway (GO:0038094) IBA
Fc-epsilon receptor signaling pathway (GO:0038095) TAS
positive regulation of mast cell degranulation (GO:0043306) IEA
neutrophil degranulation (GO:0043312) TAS
mast cell activation (GO:0045576) IEA
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  positive regulation of interleukin-10 production (GO:0032733) IEA
positive regulation of interleukin-6 production (GO:0032755) IEA
positive regulation of tumor necrosis factor production (GO:0032760) IEA
positive regulation of mast cell cytokine production (GO:0032765) IEA
References: 

How to cite this page

Fc epsilon receptors: Fc fragment of IgE receptor Ig. Last modified on 01/05/2017. Accessed on 23/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2934.