Fc fragment of IgE receptor Ig

Target id: 2934

Nomenclature: Fc fragment of IgE receptor Ig

Abbreviated Name: FCεR1γ

Family: Fc epsilon receptors

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Fc fragment of IgE receptor Ig has curated GtoImmuPdb data

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 86 1q23.3 FCER1G Fc fragment of IgE receptor Ig
Mouse 1 86 1 H3; 1 79.23 cM Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide
Rat 1 86 13q24 Fcer1g Fc fragment of IgE receptor Ig
Previous and Unofficial Names
Fc receptor, IgE, high affinity I, gamma polypeptide | Fc receptor | Fc epsilon receptor Ig | high affinity I, receptor for Fc fragment of IgE | Ly-50
Database Links
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 15 GO processes
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
GO:0002283 neutrophil activation involved in immune response IBA
GO:0002292 T cell differentiation involved in immune response IBA
GO:0030593 neutrophil chemotaxis IBA
GO:0043312 neutrophil degranulation TAS
GO:0045087 innate immune response IBA
GO:0050766 positive regulation of phagocytosis IBA
GO:0050900 leukocyte migration TAS
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GO:0001798 positive regulation of type IIa hypersensitivity IEA
GO:0001805 positive regulation of type III hypersensitivity IEA
GO:0001812 positive regulation of type I hypersensitivity IEA
GO:0002554 serotonin secretion by platelet IEA
GO:0006911 phagocytosis, engulfment IEA
GO:0043306 positive regulation of mast cell degranulation IEA
GO:0045576 mast cell activation IEA
Immuno Process:  Antigen presentation
GO Annotations:  Associated to 5 GO processes
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II IBA
GO:0031623 receptor internalization ISS
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I IBA
GO:0050766 positive regulation of phagocytosis IBA
click arrow to show/hide IEA associations
GO:0006911 phagocytosis, engulfment IEA
Immuno Process:  T cell (activation)
GO Annotations:  Associated to 5 GO processes
GO:0002292 T cell differentiation involved in immune response IBA
GO:0016064 immunoglobulin mediated immune response IBA
click arrow to show/hide IEA associations
GO:0001798 positive regulation of type IIa hypersensitivity IEA
GO:0001805 positive regulation of type III hypersensitivity IEA
GO:0001812 positive regulation of type I hypersensitivity IEA
Immuno Process:  B cell (activation)
GO Annotations:  Associated to 4 GO processes
GO:0016064 immunoglobulin mediated immune response IBA
click arrow to show/hide IEA associations
GO:0001798 positive regulation of type IIa hypersensitivity IEA
GO:0001805 positive regulation of type III hypersensitivity IEA
GO:0001812 positive regulation of type I hypersensitivity IEA
Immuno Process:  Immune regulation
GO Annotations:  Associated to 11 GO processes
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
GO:0002431 Fc receptor mediated stimulatory signaling pathway IBA
GO:0019767 IgE receptor activity IBA
GO:0038094 Fc-gamma receptor signaling pathway IBA
GO:0038095 Fc-epsilon receptor signaling pathway TAS
click arrow to show/hide IEA associations
GO:0001798 positive regulation of type IIa hypersensitivity IEA
GO:0001805 positive regulation of type III hypersensitivity IEA
GO:0001812 positive regulation of type I hypersensitivity IEA
GO:0032765 positive regulation of mast cell cytokine production IEA
GO:0033026 negative regulation of mast cell apoptotic process IEA
GO:0043306 positive regulation of mast cell degranulation IEA
Immuno Process:  Immune system development
GO Annotations:  Associated to 1 GO processes
GO:0002292 T cell differentiation involved in immune response IBA
Immuno Process:  Chemotaxis & migration
GO Annotations:  Associated to 2 GO processes
GO:0030593 neutrophil chemotaxis IBA
GO:0050900 leukocyte migration TAS
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 10 GO processes
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
GO:0002283 neutrophil activation involved in immune response IBA
GO:0002292 T cell differentiation involved in immune response IBA
GO:0002431 Fc receptor mediated stimulatory signaling pathway IBA
GO:0019767 IgE receptor activity IBA
GO:0038094 Fc-gamma receptor signaling pathway IBA
GO:0038095 Fc-epsilon receptor signaling pathway TAS
GO:0043312 neutrophil degranulation TAS
click arrow to show/hide IEA associations
GO:0043306 positive regulation of mast cell degranulation IEA
GO:0045576 mast cell activation IEA
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 4 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0032733 positive regulation of interleukin-10 production IEA
GO:0032755 positive regulation of interleukin-6 production IEA
GO:0032760 positive regulation of tumor necrosis factor production IEA
GO:0032765 positive regulation of mast cell cytokine production IEA

How to cite this page

Fc epsilon receptors: Fc fragment of IgE receptor Ig. Last modified on 01/05/2017. Accessed on 21/04/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2934.