RyR3 | Ryanodine receptors | IUPHAR/BPS Guide to PHARMACOLOGY

RyR3

Target id: 749

Nomenclature: RyR3

Family: Ryanodine receptors

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for RyR3 in GtoImmuPdb

Gene and Protein Information
Species TM P Loops AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 0 - 15q14-q15 RYR3 ryanodine receptor 3
Mouse - 0 - 2 E5-F3 Ryr3 ryanodine receptor 3
Rat - 0 - 3q34 Ryr3 ryanodine receptor 3
Previous and Unofficial Names
ryanodine receptor 3 | calcium release channel isoform 3
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Functional Characteristics
Ca2+: (P Ca/P K6) single-channel conductance: 140 pS (50mM Ca2+), 777 pS (250 mM K+)

Download all structure-activity data for this target as a CSV file

Activators
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Concentration range (M) Holding voltage (mV) Reference
caffeine Hs - - - - -
pharmacological; mM range
cytosolic Ca2+ Hs - - - - -
endogenous; μM range
cytosolic ATP Hs - - - - -
endogenous; mM range
ryanodine Hs - - - - -
pharmacological; nM - μM range
Antagonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
cytosolic Ca2+ Hs Antagonist - -
Conc range: > 1x10-3 M
cytosolic Mg2+ Hs Antagonist - -
mM range
dantrolene Hs Antagonist - -
Channel Blockers
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Affinity Units Concentration range (M) Holding voltage (mV) Reference
ruthenium red Hs - - - - -

How to cite this page

Ryanodine receptors: RyR3. Last modified on 28/07/2017. Accessed on 17/11/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=749.