ABCC2

Target id: 780

Nomenclature: ABCC2

Abbreviated Name: MRP2, cMOAT

Systematic Nomenclature: ABCC2

Family: ABCC subfamily

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for ABCC2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - ABCC2 ATP binding cassette subfamily C member 2
Mouse - - Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Rat - - Abcc2 ATP binding cassette subfamily C member 2
Previous and Unofficial Names
Canalicular multidrug resistance protein | CMOAT | cMRP | DJS | MRP2 | ATP-binding cassette, sub-family C (CFTR/MRP) member 2 | canalicular multispecific organic anion transporter | multidrug resistance associated protein 2 | multidrug resistance protein 2 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2
Database Links
DrugBank Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
PAK-104P Hs Inhibition 5.4 pKi 1
pKi 5.4 (Ki 3.7x10-6 M) [1]

References

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1. Chen ZS, Kawabe T, Ono M, Aoki S, Sumizawa T, Furukawa T, Uchiumi T, Wada M, Kuwano M, Akiyama SI. (1999) Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter. Mol. Pharmacol.56 (6): 1219-28. [PMID:10570049]

Contributors

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How to cite this page

Mary Vore.
ABCC subfamily: ABCC2. Last modified on 16/09/2015. Accessed on 21/09/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=780.