Angiotensin receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The actions of angiotensin II (AGT, P01019) (Ang II) are mediated by AT1 and AT2 receptors (nomenclature agreed by the NC-IUPHAR Subcommittee on Angiotensin Receptors; [9]), which have around 30% sequence similarity. Endogenous ligands are angiotensin II (AGT, P01019) and angiotensin III (AGT, P01019) (Ang III), while angiotensin I (AGT, P01019) is weakly active in some systems.

Receptors

AT1 receptor Show summary » More detailed page

AT2 receptor Show summary » More detailed page

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Angiotensin receptors. Accessed on 26/07/2014. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=6.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA and Harmar AJ, CGTP Collaborators. (2013) The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors. Br J Pharmacol. 170: 1459–1581.