Angiotensin receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The actions of angiotensin II (AGT, P01019) (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin Receptors [10]), which have around 30% sequence similarity. Endogenous ligands are angiotensin II (AGT, P01019) and angiotensin III (AGT, P01019) (Ang III), while angiotensin I (AGT, P01019) is weakly active in some systems.


AT1 receptor Show summary » More detailed page

AT2 receptor Show summary » More detailed page


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Further reading

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Sadashiva Karnik, Kenneth E. Bernstein, Jacqueline Kemp, Satoru Eguchi, Emanuel Escher, László Hunyady, Kalyan Tirupula, Patrick Vanderheyden, Hamiyet Unal, Marc de Gasparo, Walter (Wally) Thomas, Wayne Alexander, Kevin J. Catt, Theodore L. Goodfriend, Mastgugu Horiuchi, Ahsan Husain, Tadashi Inagami, Pieter B. M. W. M. Timmermans, Thomas Unger. Angiotensin receptors. Accessed on 26/11/2015. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA and Harmar AJ, CGTP Collaborators. (2013) The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors. Br J Pharmacol. 170: 1459–1581.