losartan

Ligand id: 590

Name: losartan

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 92.51
Molecular weight 422.16
XLogP 7.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
IUPAC Name
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
International Nonproprietary Names
INN number INN
6913 losartan
Synonyms
Cozaar® | DuP 753 | MK-954
Database Links
CAS Registry No. 114798-26-4 (source: DrugBank)
ChEBI CHEBI:6541
ChEMBL Ligand CHEMBL191
DrugBank Ligand DB00678
PubChem CID 3961
Search Google for chemical match using the InChIKey PSIFNNKUMBGKDQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PSIFNNKUMBGKDQ
Search PubMed clinical trials losartan
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Search UniChem for chemical match using the InChIKey PSIFNNKUMBGKDQ-UHFFFAOYSA-N
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Wikipedia Losartan
Comments
Losartan is an angiotensin II (AT2) receptor antagonist drug.