eprosartan

Ligand id: 588

Name: eprosartan

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 120.66
Molecular weight 424.15
XLogP 5.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1997))
IUPAC Name
4-[[2-butyl-5-[(E)-3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid
International Nonproprietary Names
INN number INN
7223 eprosartan
Synonyms
Eprozar® | SK-108566 | Teveten®
Database Links
CAS Registry No. 133040-01-4 (source: Scifinder)
ChEBI CHEBI:4814
ChEMBL Ligand CHEMBL813
DrugBank Ligand DB00876
GtoPdb PubChem SID 135650236
PubChem CID 5281037
Search Google for chemical match using the InChIKey OROAFUQRIXKEMV-LDADJPATSA-N
Search Google for chemicals with the same backbone OROAFUQRIXKEMV
Search PubMed clinical trials eprosartan
Search PubMed titles eprosartan
Search PubMed titles/abstracts eprosartan
Search UniChem for chemical match using the InChIKey OROAFUQRIXKEMV-LDADJPATSA-N
Search UniChem for chemicals with the same backbone OROAFUQRIXKEMV
Wikipedia Eprosartan
Comments
Eprosartan is an antagonist of the type 1 angiotensin II receptor (AGTR1).
Marketed formulations may contain eprosartan mesylate (PubChem CID 5282474).