4.2.1.1 Carbonate dehydratases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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Carbonic anhydrases facilitate the interconversion of water and carbon dioxide with bicarbonate ions and protons (EC 4.2.1.1), with over a dozen gene products identified in man. The enzymes function in acid-base balance and the movement of carbon dioxide and water. They are targetted for therapeutic gain by particular antiglaucoma agents and diuretics.

Enzymes

carbonic anhydrase 1 C Show summary » More detailed page

carbonic anhydrase 4 Show summary » More detailed page

carbonic anhydrase 7 C Show summary » More detailed page

carbonic anhydrase 12 C Show summary » More detailed page

carbonic anhydrase 13 Show summary » More detailed page

carbonic anhydrase 14 Show summary » More detailed page

Further reading

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References

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How to cite this family page

Database page citation:

4.2.1.1 Carbonate dehydratases. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=842.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.