4.2.1.1 Carbonate dehydratases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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Carbonic anhydrases facilitate the interconversion of water and carbon dioxide with bicarbonate ions and protons (EC 4.2.1.1), with over a dozen gene products identified in man. The enzymes function in acid-base balance and the movement of carbon dioxide and water. They are targetted for therapeutic gain by particular antiglaucoma agents and diuretics.

Enzymes

carbonic anhydrase 1 C Show summary » More detailed page

carbonic anhydrase 4 Show summary » More detailed page

carbonic anhydrase 7 C Show summary » More detailed page

carbonic anhydrase 12 C Show summary » More detailed page

carbonic anhydrase 13 Show summary » More detailed page

carbonic anhydrase 14 Show summary » More detailed page

Further reading

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References

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How to cite this family page

Database page citation:

4.2.1.1 Carbonate dehydratases. Accessed on 25/06/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=842.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 172: 6024-6109.