carbonic anhydrase 13

Target id: 2748

Nomenclature: carbonic anhydrase 13

Family: 4.2.1.1 Carbonate dehydratases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for carbonic anhydrase 13 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 262 8q21.2 CA13 carbonic anhydrase 13
Mouse - 262 3 A2 Car13 carbonic anhydrase 13
Rat - 262 2q23 Car13 carbonic anhydrase 13
Previous and Unofficial Names
carbonic anhydrase XIII
Database Links
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 4.2.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
acetazolamide Mm Inhibition 7.8 pKi 1
pKi 7.8 (Ki 1.7x10-8 M) [1]

References

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1. Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. (2010) Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg. Med. Chem. Lett.20 (15): 4376-81. [PMID:20605094]

How to cite this page

4.2.1.1 Carbonate dehydratases: carbonic anhydrase 13. Last modified on 30/03/2016. Accessed on 24/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2748.