carbonic anhydrase 13 | Carbonic anhydrases | IUPHAR/BPS Guide to PHARMACOLOGY

Top ▲

carbonic anhydrase 13

Target not currently curated in GtoImmuPdb

Target id: 2748

Nomenclature: carbonic anhydrase 13

Abbreviated Name: CA XIII

Family: Carbonic anhydrases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 262 8q21.2 CA13 carbonic anhydrase 13
Mouse - 262 3 A2 Car13 carbonic anhydrase 13
Rat - 262 2q23 Car13 carbonic anhydrase 13
Previous and Unofficial Names
carbonic anhydrase XIII
Database Links
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 4.2.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
acetazolamide Mm Inhibition 7.8 pKi 1
pKi 7.8 (Ki 1.7x10-8 M) [1]

References

Show »

1. Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. (2010) Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg. Med. Chem. Lett., 20 (15): 4376-81. [PMID:20605094]

How to cite this page

Carbonic anhydrases: carbonic anhydrase 13. Last modified on 29/11/2018. Accessed on 08/12/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2748.