galmic [Ligand Id: 6119] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1187471 (Galmic)
  • GAL1 receptor/Galanin receptor 1 in Human [ChEMBL: CHEMBL4894] [GtoPdb: 243] [UniProtKB: P47211]
There should be some charts here, you may need to enable JavaScript!
  • GAL2 receptor/Galanin receptor 2 in Rat [ChEMBL: CHEMBL5577] [GtoPdb: 244] [UniProtKB: O08726]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAL1 receptor/Galanin receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4894] [GtoPdb: 243] [UniProtKB: P47211]
ChEMBL Binding affinity to human GalR1 B 4.47 pKi 34200 nM Ki J Med Chem (2010) 53: 1871-1875 [PMID:20121116]
GtoPdb - - 4.47 pKi 34200 nM Ki Neuropeptides (2005) 39: 161-3 [PMID:15944006];
Proc Natl Acad Sci USA (2004) 101: 10470-5 [PMID:15240875]
GAL2 receptor/Galanin receptor 2 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5577] [GtoPdb: 244] [UniProtKB: O08726]
GtoPdb - - 5 pKd >10000 nM Kd Proc Natl Acad Sci USA (2004) 101: 10470-5 [PMID:15240875];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]
ChEMBL Binding affinity to rat GalR2 B 4 pKi >100000 nM Ki J Med Chem (2010) 53: 1871-1875 [PMID:20121116]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]