progesterone

Ligand id: 2377

Name: progesterone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 34.14
Molecular weight 314.22
XLogP 4.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1959))
IUPAC Name
(8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
417 progesterone
Synonyms
Prometrium®
Utrogestan®
Database Links
CAS Registry No. 57-83-0 (source: Scifinder)
ChEBI CHEBI:17026
ChEMBL Ligand CHEMBL103
DrugBank Ligand DB00396
Human Metabolome Database HMDB01830
Lipid Maps LMST02030159
NURSA Ligand 10.1621/E7EEFRDJA5
PharmGKB Drug PA451123
PubChem CID 5994
RCSB PDB Ligand STR&sid=2AA5
Search Google for chemical match using the InChIKey RJKFOVLPORLFTN-LEKSSAKUSA-N
Search Google for chemicals with the same backbone RJKFOVLPORLFTN
Search PubMed clinical trials progesterone
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Wikipedia Progesterone
Comments
Progesterone is an endogenous steroid and progestogen sex hormone. It is the major progestogen and is required for the production of other endogenous steroids, including the sex hormones and corticosteroids.