nortriptyline

Ligand id: 2404

Name: nortriptyline

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 12.03
Molecular weight 263.17
XLogP 8.04
No. Lipinski's rules broken 1

Molecular properties generated using the CDK
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1964))
IUPAC Name
methyl({3-[(2E)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]propyl})amine
International Nonproprietary Names
INN number INN
1328 nortriptyline
Synonyms
Aventyl® | nortriptyline hydrochloride | Pamelor®
Comments
Nortriptyline is a second-generation tricyclic antidepressant (TCA).
Database Links
BindingDB Ligand 50020710
CAS Registry No. 72-69-5 (source: DrugBank)
ChEBI CHEBI:7640
ChEMBL Ligand CHEMBL445
DrugBank Ligand DB00540
GtoPdb PubChem SID 135650736
PubChem CID 4543
RCSB PDB Ligand 21B
Search Google for chemical match using the InChIKey PHVGLTMQBUFIQQ-UHFFFAOYSA-N
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Search PubMed clinical trials nortriptyline
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Search UniChem for chemical match using the InChIKey PHVGLTMQBUFIQQ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PHVGLTMQBUFIQQ
Wikipedia Nortriptyline