drospirenone

Ligand Id: 2874
Ligand name drospirenone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 43.37
Molecular weight 366.22
XLogP 4.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
(1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19}.0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione
International Nonproprietary Names
INN number INN
6519 drospirenone
Synonyms
dihydrospirorenone
Yasmin®
ZK30595
Database Links
CAS Registry No. 67392-87-4
ChEMBL Ligand CHEMBL1509
DrugBank Ligand DB01395
PubChem CID 68873
Search Google for chemical match using the InChIKey METQSPRSQINEEU-HXCATZOESA-N
Search Google for chemicals with the same backbone METQSPRSQINEEU
Search PubMed clinical trials drospirenone
Search PubMed titles drospirenone
Search PubMed titles/abstracts drospirenone
Wikipedia Drospirenone
Comments
Drospirenone is a synthetic analog of spironolactone. As a contraceptive agent it is used for its progestin-like activity, but it also has anti-androgen and anti-mineralocorticoid properties.