memantine

Ligand id: 4253

Name: memantine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 26.02
Molecular weight 179.17
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2003))
IUPAC Name
3,5-dimethyladamantan-1-amine
International Nonproprietary Names
INN number INN
3952 memantine
Synonyms
Namenda®
Database Links
CAS Registry No. 19982-08-2 (source: Scifinder)
ChEMBL Ligand CHEMBL807
DrugBank Ligand DB01043
GtoPdb PubChem SID 178101070
PubChem CID 4054
Search Google for chemical match using the InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
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Search PubMed clinical trials memantine
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Search UniChem for chemical match using the InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BUGYDGFZZOZRHP
Wikipedia Memantine
Comments
Memantine is a non-competitive NMDA receptor antagonist approved for Alzheimer's disease but is also being studied in non-dementia psychiatric disorders [1] .