isradipine

Ligand id: 4488

Name: isradipine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 103.55
Molecular weight 371.15
XLogP 3.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1990))
IUPAC Name
O5-methyl O3-propan-2-yl 4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
5724 isradipine
Synonyms
(±)-isradipine | DynaCirc® | PN-200-110 | Prescal®
Database Links
CAS Registry No. 75695-93-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1648
DrugBank Ligand DB00270
GtoPdb PubChem SID 178101216
PubChem CID 3784
Search Google for chemical match using the InChIKey HMJIYCCIJYRONP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HMJIYCCIJYRONP
Search PubMed clinical trials isradipine
Search PubMed titles isradipine
Search PubMed titles/abstracts isradipine
Search UniChem for chemical match using the InChIKey HMJIYCCIJYRONP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HMJIYCCIJYRONP
Wikipedia Isradipine
Comments
The approved drug isradipine is a racemic mixture of (+)-isradipine and (-)-isradipine. We show the non-stereo molecule to represent the mixture.