growth arrest specific protein 6

Ligand id: 4935

Name: growth arrest specific protein 6

Abbreviated name: Gas6

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
GAS6 growth arrest specific 6 Human prepro-growth arrest-specific 6 AXLLG, AXL stimulatory factor, AXSF, DKFZp666G247, FLJ34709, growth arrest-specific 6
Synonyms
AXL receptor tyrosine kinase ligand
Database Links
CATH/Gene3D 4.10.740.10
Ensembl Gene ENSG00000183087 (Hs)
Human Protein Atlas ENSG00000183087 (Hs)
UniProtKB Q14393 (Hs)
Wikipedia GAS6
Comments
GAS6 is the sole ligand for AXL receptor tytrosine kinase. Because of AXL's roles in cancer, fibrosis and viral infection, GAS6 has emerged as an attractive target for drug development.